Научно-исследовательский институт клинической хирургии

Институт занимается разраборткой и внедрением новых методов клинической хирургии в различных областях медицины.

Избранные публикации


  • Gavrilov S.G., Moskalenko Y.P. Does pelvic congestion syndrome influence symptoms of chronic venous disease of the lower extremities?. European Journal of Obstetrics & Gynecology and Reproductive Biology. 12.2019; (243):83-86.
  • Sazhin A., Zolotukhin I., Seliverstov E., Nikishkov A., Shevtsov Yu., Andriyashkin A., Tatarintsev A., Kirienko A. Prevalence and risk factors for abdominal wall hernia in the general Russian population. Hernia : the journal of hernias and abdominal wall surgery. 12.2019; 23(6):1237-1242.
  • Gavrilov S.G., Efremova O.I. Surgical aspects of venous pelvic pain treatment. Current Medical Research and Opinion. 10.2019; 35(11):1983-1989.
  • Gavrilov S.G., Moskalenko Y.P., Karalkin A.V. Effectiveness and safety of micronized purified flavonoid fraction for the treatment of concomitant varicose veins of the pelvis and lower extremities. Current Medical Research and Opinion. 05.2019; 35(6):1019–1026.
  • Zolotukhin I., Seliverstov E., Shevtsov Y., Avakiants I., Tatarintsev A., Kirienko A. Risk factors for venous symptoms in Russian patients with chronic venous disease. Current Medical Research and Opinion. 04.2019; 35(9):1583-1587.
  • Kirienko A., Radak D., Maggioli A. Clinical efficacy of once-daily micronized purified flavonoid fraction 1000 mg tablet in patients with symptomatic chronic venous disease. Current Medical Research & Opinion. 03.2019; 35(3):553-557.
  • Gavrilov S.G., Lebedev I.S. Is the endovascular embolization of tributaries of the internal iliac veins essential in the treatment of isolated pelvic-perineal reflux?. Current Medical Research and Opinion. 01.2019; 35(1):27-31.


  • Shadrina A., Voronina E., Smetanina M., Tsepilov Y., Sevost'ianova K., Shevela A., Seliverstov E., Zakharova E., Ilyukhin E., Kirienko A., Zolotukhin I., Filipenko M. Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians. Immunologic Research. 01.2018 ; (66(1)):141-150. DOI: 10.1007/s12026-017-8981-4
  • Shadrinaa A., Tsepilovc Y., Sokolovaa E., Smetaninaa M., Voroninaa E., Pakhomovb E., Sevost'ianovaa K., Shevelaa A., Ilyukhind E., Seliverstove E., Zolotukhin I., Filipenko M. Genome-wide association study in ethnic Russians suggests an association of the MHC class III genomic region with the risk of primary varicose veins. Gene. 06.2018 ; (659):93–99. DOI: 10.1016/j.gene.2018.03.039
  • Shadrina A., Tsepilov Y., Smetanina M., VoroninaE., Seliverstov E., Ilyukhin E., Kirienko A., Zolotukhin I., Filipenko M. Polymorphisms of genes involved in inflammation and blood vessel development influence the risk of varicose veins. Clinical Genetics. 04.2018; 94(2):191-199. DOI: 10.1111/cge.13362
  • Smetanina M.A., Kel A.E., Sevost'ianova K.S., Maiborodin I.V., Shevela A.I., Zolotukhin I.A., Stegmaier P., Filipenko M.L. DNA methylation and gene expression profiling reveal MFAP5 as a regulatory driver of extracellular matrix remodeling in varicose vein disease. Epigenomics. 07.2018; 10(8):1103-1119. DOI:10.2217/epi-2018-0001
  • Gankovskaya L.V., Bykova V.P., Namazova-baranova L.S., Karaulov A.V., Rahmanova I.V., Gankovskii V.A., Merkushova C.D., Svitich O.A. Innate immunity gene expression by epithelial cells of upper respiratory tract in children with adenoid hypertrophy. Auris Nasus Larynx. 04.2018; 45(4):753-759. DOI: 10.1016/j.anl.2017.11.011
  • Bogomilsky M.R., Rakhmanova I.V., Ishanova Yu.S., Matroskin A.G., Shelamova V.N. The importance of audiological-logopedic monitoring in premature of the first year. Znanstvena misel. 10.2018; 1(17):38-44


  • Gavrilov S.G., Turischeva O.O. Conservative treatment of pelvic congestion syndrome: indications and opportunities. Current Medical Research & Opinion. 03.2017; 33(3):1099-1103. DOI: 10.1080/03007995.2017.1302414
  • Gavrilov S.G., Karalkin A.V., Turischeva O.O. Compression treatment of pelvic congestion syndrome. Phlebology. 06.2017 ; (22):1-7. DOI: 10.1177/0268355517717424
  • Gavrilov S.G. Vulvar varicosities: diagnosis, treatment, and prevention. Journal of Women's Health. 06.2017 ; (9):463-475. DOI: 10.2147/IJWH.S126165
  • D'yakonova I.N., Kamkina O.V., Rakhmanova I.V., Ishanova Y.S., Burmistrova D.S. Effect of Successive Administration of Vancomycin and Amikacin on Auditory Function of Immature Animals. Bulletin of Experimental Biology and Medicine. 02.2017; 162(4):458-461. DOI: 10.1007/s10517-017-3639-8
  • Shadrina A.S, Smetanina M.A, Sevost'ianova K.S, Voronina E.N, Filipenko M.L, Seliverstov E.I, Zolotukhin I.A., Ilyukhin E.A. Functional polymorphism RS1024611 in the MCP1 gene is associated with the risk of varicose veins of lower extremities. Journal of Vascular Surgery: Venous and Lymphatic Disorders. 06.2017; 5(4):561-566
  • Shadrinaa А., Smetaninaa М., Sokolova E. , Sevost'ianova K., Shevela A., Seliverstov E., Zakharova E., Ilyukhin E., Voronina E., Makarov D., Kirienko A., Zolotukhin I., Filipenko M. Top SNPs from the phenome-wide association study catalog and the risk of varicose veins of lower extremities: A replication study. Meta Gene. 07.2017 ; (12):47–49
  • Shadrina A.S., Smetanina M.A., Sevost’yanova K.S., Shevela A.I., Seliverstov E.I., Zakharova E.A., Voronina E.N., IlyukhinI E.A., Zolotukhin I.A., Kirienko A.I., Filipenko M.L. Polymorphism of Matrix Metalloproteinases Genes MMP1, MMP2, MMP3, and MMP7 and the Risk of Varicose Veins of Lower Extremities. Bulletin of Experimental Biology and Medicine. 09.2017; 163(5):650-654
  • Zolotukhin I.A., Seliverstov E.I., Shevtsov Y.N., Avakiants I.P., Nikishkov A.S., Tatarintsev A.M., Kirienko F.I. Prevalence and Risk Factors for Chronic Venous Disease in the General Russian Population. European Journal of Vascular and Endovascular Surgery. 12.2017; 54(6):752–758. DOI: 10.1016/j.ejvs.2017.08.033
  • Solodova R.F., Galatenko V.V., Nakashidze E.R., Shapovalyants S.G., Andreytsev I.L., Sokolov M.E., Podolskii V.E. Instrumental Mechanoreceptoric Palpation in Gastrointestinal Surgery. Minimally Invasive Surgery. 12.2017; 2017(12):1-6. DOI: 10.1155/2017/6481856


  • Shadrina A., Voronina E., Zolotukhin I., Filipenko M. Allele and genotype frequencies of polymorphisms in cytokine genes in ethnic Russian individuals from Moscow, Russia. Human Immunology. 11.2016; 78(2):190-191. DOI: 10.1016/j.humimm.2016.11.007
  • Yakovleva E.G., Korotkov K.G., Fedorov E.D., Ivanova E.V., Plahov R.V., Belonosov S.S. Engineering Approach to Identifying Patients with Colon Tumors on the Basis of Electrophotonic Imaging Technique Data. Open Biomedical Engineering Journal. 06.2016 ; (10):72-80. DOI: 10.2174/1874120701610010072


  • Dobrokhotova J., Grishin I., Khachatryan A., Causeva O., Zlatovratsky A., Rogovskaya S. Uterine Artery Embolisation for the Treatment of Large Submucosal Fibroid (Clinical Case). Obstetrics and Gynaecology Cases-Reviews. 05.2015; 2(1):1−4.
  • Yakovleva E.G., Buntseva O.A., Belonosov S.S., Fedorov E.D., Korotkov K., Zarubina T.V. Identifying patients with colon neoplasias with gas discharge visualization technique. Journal of Alternative and Complementary Medicine. 11.2015; 21(11):720-724. DOI: 10.1089/acm.2014.0168
  • Zolotukhin I., Seliverstov E., Khabazova K., An E., Lebedev I. Endovenous laser ablation of incompetent calf perforating veins does not prevent recurrence of venous ulcers in patients with post-thrombotic syndrome. Phlebological Review. 11.2015; 23(2):54-59. DOI: 10.5114/pr.2015.54036